| Safety and efficacy of clomiphene citrate and L-carnitine in idiopathic male infertility: a comparative study. | |
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MedLine Citation:
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PMID: 20845296 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: To compare the effects of L-carnitine with clomiphene citrate in idiopathic infertile men. MATERIALS AND METHODS: Fifty-two men with idiopathic infertility were recruited in this randomized controlled trial. They were randomly assigned into 2 treatment groups, group 1 (n = 20) and group 2 (n = 32), who received L-carnitine 25 mg/day and clomiphene citrate 2 gr/day, respectively, for a period of 3 months. RESULTS: Comparing the effect of L-carnitine and clomiphene on sperm parameters before and after the treatment, both medications had influence on sperm count and motility (P = .01). L-carnitine significantly increased the semen volume (P = .001), while clomiphene citrate was significantly associated with the motility percentage and normal morphology (P = .008). CONCLUSION: It seems that the use of clomiphene citrate and L-carnitine, either individually or in combination, as the first step of idiopathic male infertility treatment is reasonable, safe, and effective. |
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Authors:
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Mahmoudreza Moradi; Asaad Moradi; Mohsen Alemi; Hassan Ahmadnia; Hossein Abdi; Alireza Ahmadi; Shahrzad Bazargan-Hejazi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Urology journal Volume: 7 ISSN: 1735-546X ISO Abbreviation: Urol J Publication Date: 2010 |
Date Detail:
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Created Date: 2010-09-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101286676 Medline TA: Urol J Country: Iran |
Other Details:
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Languages: eng Pagination: 188-93 Citation Subset: IM |
Affiliation:
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Fertility-Infertility Research Center, Urology and Nephrology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. drmrmoradi@yahoo.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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