| Safety of drug-eluting stents. | |
| | |
MedLine Citation:
|
PMID: 21389909 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Significant evolution in catheter-based technologies for percutaneous coronary intervention has occurred since the introduction of coronary balloon angioplasty by Andreas Grüntzig in 1977. As balloon angioplasty was supplanted by bare metal stents and subsequently drug-eluting stents (DES), randomized comparative clinical trials have demonstrated a progressive decline in both angiographic and clinical restenosis with each technologic iteration. Following widespread clinical use of DES, multiple safety issues have been identified in late follow-up that have prompted efforts toward development of bioresorbable polymers and polymer-free metal platforms, as well as completely resorbable DES platforms. The ultimate goal of these efforts is to provide safe and durable coronary patency. The promise of bioresorbable DES platforms includes the additional benefits of recovery in normal autoregulatory as well as microvascular function, the capacity for late luminal enlargement/expansive remodeling, and the potential for reducing the requirement for prolonged dual antiplatelet therapy. |
| | |
Authors:
|
Dean J Kereiakes |
Related Documents
:
|
22725949 - Assessing acute coronary syndrome patients' cardiac-related beliefs, motivation and moo... 21708399 - Influence of cardiac resynchronization therapy on indices of inflammation, the prothrom... 21876429 - Persistence of mortality risk in patients with acute cardiac diseases and mild thyroid ... 22858369 - Effect of transfer delay on left ventricular function after primary pci for st elevatio... 22410839 - Pet and mri for the evaluation of regional myocardial perfusion and wall thickening aft... 21609389 - Optimizing cardiac resynchronization therapy in advanced heart failure. 6634519 - Aggressive management of ventricular arrhythmias. with newer techniques to predict drug... 11208449 - Effectiveness of high resolution ecg spectral analysis in discrimination of patients pr... 23188629 - What is the value of stress (99m)tc-tetrofosmin myocardial perfusion imaging for the as... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Reviews in cardiovascular medicine Volume: 11 ISSN: 1530-6550 ISO Abbreviation: Rev Cardiovasc Med Publication Date: 2010 |
Date Detail:
|
Created Date: 2011-03-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100960007 Medline TA: Rev Cardiovasc Med Country: United States |
Other Details:
|
Languages: eng Pagination: 186-200 Citation Subset: IM |
Affiliation:
|
The Christ Hospital Heart and Vascular Center, The Lindner Research Center, Cincinnati, OH. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Synthesis and antimicrobial evaluation of some heterocyclic chalcone derivatives.
Next Document: Medical management of hypertrophic cardiomyopathy.