Document Detail

Safety of dobutamine stress transesophageal echocardiography in obese patients for evaluation of potential ischemic heart disease.
MedLine Citation:
PMID:  15488087     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine the safety of dobutamine stress transesophageal echocardiography (DS-TEE) in the evaluation of potential coronary artery disease in obese patients. Obese patients tend to have a higher prevalence of hypertension, coronary artery disease, and sleep apnea conditions that could potentially predispose to complications during endoscopic procedures such as DS-TEE. In addition, obese patients are more likely to have oxygen desaturation during upper gastrointestinal endoscopy. Thus, the safety of DS-TEE in 90 obese patients (body mass index (BMI) > or = 27.5 kg/m2) and 86 nonobese patients (BMI < 27.5 kg/m2) was compared. Minor complications (i.e., complications of transient duration and requiring no or only simple intervention) occurred with almost equal frequency in the nonobese and obese groups (28% vs. 29%, P = ns). Transient hypotension was observed in 9% of the obese group compared to 22% in the nonobese group (P < 0.025). However, transient hypertension was noted in 20% of the obese patients compared to 6% in the nonobese group (P < 0.01). A major complication occurred in three obese patients (3.3%), which included hypotension, marked elevation of systolic blood pressure, or ventricular fibrillation. Four patients (4.7%, P = ns) of the nonobese group had a major complication, which included sustained ventricular tachycardia in one, hypertension in one, and hypotension in two patients. No deaths occurred in either group. Although obesity should remain a consideration in the risk assessment of whether or not to perform DS-TEE, when proper precautions are instituted DS-TEE appears equally safe in obese as compared to nonobese patients.
Tariq S Siddiqui; Marcus F Stoddard
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  21     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-18     Completed Date:  2006-08-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  603-8     Citation Subset:  IM    
Department of Medicine, Division of Cardiology, University of Louisville, Louisville, Kentucky 40292, USA.
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MeSH Terms
Blood Pressure
Body Mass Index
Echocardiography, Stress / adverse effects*
Echocardiography, Transesophageal / adverse effects*
Equipment Safety
Middle Aged
Multivariate Analysis
Myocardial Ischemia / epidemiology,  physiopathology*,  ultrasonography*
Obesity / epidemiology,  physiopathology*,  ultrasonography*
Oxygen Consumption
Predictive Value of Tests
Severity of Illness Index
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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