Document Detail

Safety assessment of xylene sulfonic Acid, toluene sulfonic Acid, and alkyl aryl sulfonate hydrotropes as used in cosmetics.
MedLine Citation:
PMID:  22247238     Owner:  NLM     Status:  In-Data-Review    
Xylene sulfonic acid, toluene sulfonic acid, and alkyl aryl sulfonate hydrotropes used in cosmetics as surfactants, hydrotropes, were reviewed in this safety assessment. The similar structure, properties, functions, and uses of these ingredients enabled grouping them and using the available toxicological data to assess the safety of the entire group. The Cosmetic Ingredient Review Expert Panel reviewed relevant animal and human data related to these ingredients. The panel concluded that xylene sulfonic acid and alkyl aryl sulfonate hydrotropes are safe as cosmetic ingredients in the present practices of use and concentrations as described in this safety assessment, when formulated to be nonirritating.
Wilma F Bergfeld; Donald V Belsito; Curtis D Klaassen; Ronald Hill; Daniel Liebler; James G Marks; Ronald C Shank; Thomas J Slaga; Paul W Snyder; F Alan Andersen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of toxicology     Volume:  30     ISSN:  1092-874X     ISO Abbreviation:  Int. J. Toxicol.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-01-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708436     Medline TA:  Int J Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  270S-83S     Citation Subset:  IM    
Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 412, Washington, DC 20036, USA Email:
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