Document Detail


Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics.
MedLine Citation:
PMID:  23696578     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The Cosmetic Ingredient Review Expert Panel assessed the safety of triethanolamine (TEA) and 31 related TEA-containing ingredients as used in cosmetics. The TEA is reported to function as a surfactant or pH adjuster; the related TEA-containing ingredients included in this safety assessment are reported to function as surfactants and hair- or skin-conditioning agents. The exception is TEA-sorbate, which is reported to function as a preservative. The Panel reviewed the available animal and clinical data. Although data were not available for all the ingredients, the panel relied on the information available for TEA in conjunction with previous safety assessments of components of TEA-containing ingredients. These data could be extrapolated to support the safety of all included ingredients. The panel concluded that TEA and related TEA-containing ingredients named in this report are safe as used when formulated to be nonirritating. These ingredients should not be used in cosmetic products in which N-nitroso compounds can be formed.
Authors:
Monice M Fiume; Bart Heldreth; Wilma F Bergfeld; Donald V Belsito; Ronald A Hill; Curtis D Klaassen; Daniel Liebler; James G Marks; Ronald C Shank; Thomas J Slaga; Paul W Snyder; F Alan Andersen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of toxicology     Volume:  32     ISSN:  1092-874X     ISO Abbreviation:  Int. J. Toxicol.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-05-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708436     Medline TA:  Int J Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59S-83S     Citation Subset:  IM    
Affiliation:
Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 412, Washington, DC 20036, USA. Email: cirinfo@cir-safety.org.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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