Document Detail

Safety aspects of spinal cord stimulation in severe angina pectoris.
MedLine Citation:
PMID:  7866604     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Spinal cord stimulation has been used over the past decade for the treatment of patients suffering from intractable angina pectoris, despite having received optimal medical therapy, and who are unsuitable for further surgical intervention. The clinical results are promising and several studies have shown that the antianginal effect of the treatment is associated with a reduction in myocardial ischemia. It has been suggested, however, that spinal cord stimulation may only attenuate the transmission of pain from the heart, without influencing myocardial ischemia. This is a major safety concern when applying this treatment strategy. METHODS: The aim of this study was to assess the potentially unfavourable aspects of spinal cord stimulation in patients with severe coronary artery disease and angina pectoris by means of repeated long-term ECG recordings. Nineteen patients who had been accepted for implantation of spinal cord stimulators for the treatment of severe angina pectoris were included. RESULTS: No increases were noted in the frequency of ischemic episodes, the total ischemic burden, or the number of arrhythmic episodes during treatment. CONCLUSION: The results of this study do not indicate any unfavourable effects of spinal cord stimulation in severe angina pectoris in terms of an increase in the frequency or severity of myocardial ischemia during treatment with spinal cord stimulation.
T Eliasson; S Jern; L E Augustinsson; C Mannheimer
Related Documents :
10995414 - Plasma n terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unsta...
11016014 - Susceptibility of apolipoprotein b-containing lipoproteins to oxidation and antioxidant...
21169284 - Occurrence of left-sided heart valve involvement before right-sided heart valve involve...
2340644 - Hypothesis: ischaemic plaque necrosis as the initiator of unstable angina/acute myocard...
24276124 - An allosteric modulator of the adenosine a1 receptor improves cardiac function followin...
11712654 - Characterisation of acute myocardial ischaemia in a canine model based on principal com...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Coronary artery disease     Volume:  5     ISSN:  0954-6928     ISO Abbreviation:  Coron. Artery Dis.     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-03-30     Completed Date:  1995-03-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9011445     Medline TA:  Coron Artery Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  845-50     Citation Subset:  IM    
Department of Internal Medicine, Ostra Hospital, Göteborg, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angina Pectoris / complications,  physiopathology,  therapy*
Arrhythmias, Cardiac / etiology
Coronary Disease / etiology*,  physiopathology
Electric Stimulation Therapy / adverse effects*
Heart Rate
Middle Aged
Pain / therapy*
Spinal Cord

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Discordance of anti-ischemic and hemodynamic effects of captopril in stable coronary artery disease.
Next Document:  Aluminium phthalocyanines-induced photolysis of human vascular wall cells in culture and the effect ...