Document Detail


Safety aspects of spinal cord stimulation in severe angina pectoris.
MedLine Citation:
PMID:  7866604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Spinal cord stimulation has been used over the past decade for the treatment of patients suffering from intractable angina pectoris, despite having received optimal medical therapy, and who are unsuitable for further surgical intervention. The clinical results are promising and several studies have shown that the antianginal effect of the treatment is associated with a reduction in myocardial ischemia. It has been suggested, however, that spinal cord stimulation may only attenuate the transmission of pain from the heart, without influencing myocardial ischemia. This is a major safety concern when applying this treatment strategy. METHODS: The aim of this study was to assess the potentially unfavourable aspects of spinal cord stimulation in patients with severe coronary artery disease and angina pectoris by means of repeated long-term ECG recordings. Nineteen patients who had been accepted for implantation of spinal cord stimulators for the treatment of severe angina pectoris were included. RESULTS: No increases were noted in the frequency of ischemic episodes, the total ischemic burden, or the number of arrhythmic episodes during treatment. CONCLUSION: The results of this study do not indicate any unfavourable effects of spinal cord stimulation in severe angina pectoris in terms of an increase in the frequency or severity of myocardial ischemia during treatment with spinal cord stimulation.
Authors:
T Eliasson; S Jern; L E Augustinsson; C Mannheimer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Coronary artery disease     Volume:  5     ISSN:  0954-6928     ISO Abbreviation:  Coron. Artery Dis.     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-03-30     Completed Date:  1995-03-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9011445     Medline TA:  Coron Artery Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  845-50     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Ostra Hospital, Göteborg, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Aged
Angina Pectoris / complications,  physiopathology,  therapy*
Arrhythmias, Cardiac / etiology
Coronary Disease / etiology*,  physiopathology
Electric Stimulation Therapy / adverse effects*
Electrocardiography
Female
Heart Rate
Humans
Male
Middle Aged
Pain / therapy*
Spinal Cord

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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