Document Detail

Safety of antiviral medication for the treatment of herpes during pregnancy.
MedLine Citation:
PMID:  21490353     Owner:  NLM     Status:  MEDLINE    
QUESTION: One of my patients is a pregnant woman in her first trimester with a history of recurrent genital herpes. She is concerned about whether use of her antiviral medication will adversely affect her baby. What should I tell her?
ANSWER: Studies have shown that the use of acyclovir or valacyclovir is not associated with an increase in birth defects. Limited data exist for famciclovir and therefore it would not be considered a first-line choice for treatment of herpes during pregnancy.
So-Hee Kang; Angela Chua-Gocheco; Pina Bozzo; Adrienne Einarson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian family physician Médecin de famille canadien     Volume:  57     ISSN:  1715-5258     ISO Abbreviation:  Can Fam Physician     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-14     Completed Date:  2011-09-01     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  427-8     Citation Subset:  IM    
Faculty of Pharmacy, University of Toronto, Canada.
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MeSH Terms
2-Aminopurine / analogs & derivatives,  therapeutic use
Acyclovir / analogs & derivatives*,  therapeutic use*
Antiviral Agents / therapeutic use*
Herpes Genitalis / drug therapy*
Pregnancy Complications, Infectious / drug therapy*
Valine / analogs & derivatives*,  therapeutic use
Reg. No./Substance:
0/Antiviral Agents; 104227-87-4/famciclovir; 452-06-2/2-Aminopurine; 59277-89-3/Acyclovir; 7004-03-7/Valine; MZ1IW7Q79D/valacyclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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