| Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase) in Acute Ischemic Stroke. | |
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MedLine Citation:
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PMID: 22389825 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the efficacy and safety of thrombolytic therapy. Our study enrolled 23 patients out of which 2 patients died due to ICH; we also found that only 39% of patients reached hospital within stroke window, and for those treated, mean NIHSS during admission was 14.0, but drastic improvement was shown after 24 hours of treatment, that is, 9.89 (P < 0.0001), and at discharge, it was 5.1 (P < 0.0001) which showed a clear impact of the treatment, and around 60% of patients were discharged within an mRS score of 1 and 2. Hence, it was found that thrombolytic therapy was beneficial, efficacious, and safe if used within 3 to 4.5 hours. |
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Authors:
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Palanisamy Sivanandy; Binny Thomas; Vijayan Krishnan; Sumathy Arunachalam |
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Publication Detail:
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Type: Journal Article Date: 2011-11-29 |
Journal Detail:
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Title: ISRN neurology Volume: 2011 ISSN: 2090-5513 ISO Abbreviation: ISRN Neurol Publication Date: 2011 |
Date Detail:
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Created Date: 2012-03-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101568083 Medline TA: ISRN Neurol Country: Egypt |
Other Details:
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Languages: eng Pagination: 618624 Citation Subset: - |
Affiliation:
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Department of Pharmacy Practice, KMCH College of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore, Tamilnadu 48, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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