Document Detail

Sacral neuromodulation in patients with multiple sclerosis.
MedLine Citation:
PMID:  21400258     Owner:  NLM     Status:  Publisher    
PURPOSE: We present a case series of patients with multiple sclerosis (MS) and neurogenic lower urinary tract dysfunction treated by sacral neuromodulation (SNM). METHODS: We reviewed charts of 25 patients who were treated for refractory lower urinary tract symptoms; during the SNM testing phase, patient management included evaluation of number of daily voiding, number of episodes of incontinence, residual urine and quality of life score. Patients who experienced greater than 50% improvement in symptoms of frequency and incontinence episodes and/or a greater than 50% decrease in the number of catheterizations and a greater than 50% increase in voided volumes were offered placement of the permanent InterStim(TM) . RESULTS: Fifteen patients were implanted with InterStim(TM); mean duration of MS was 13.66 years; mean follow-up of patients was 49.4 months. Nine patients were on clean intermittent catheterization, and in all of them, a significant decrease in residual volume with increase in voided volume and number of voiding per day; in 6 patients, the main problem was incontinence, and in them incontinence, episodes decreased and voided volume increased. Sixty-six per cent of patients have a functioning device after a mean follow-up of 61.2 months. CONCLUSIONS: SNM is a good option in the treatment of voiding dysfunction in patients with MS in a medium to long-term follow-up. Urinary retention due to detrusor underactivity is not a good indication for SNM; it should be offered to MS patients with refractory urgency urinary incontinence and MS patients with urinary retention due to detrusor-sphincter dyssynergia (DSD).
Daniele Minardi; Giovanni Muzzonigro
Related Documents :
25176588 - Histological inflammation in ulcerative colitis in deep remission under treatment with ...
25432538 - Set-up verification and 2-dimensional electronic portal imaging device dosimetry during...
25163238 - Familial hypocalciuric hypercalcemia and calcium sensing receptor.
25196428 - Airway bacterial colonization and serum c-reactive protein are associated with chronic ...
3764698 - Candida and perforated peptic ulcers.
17712588 - Low incidence of restrictive valvulopathy in patients with parkinson's disease on moder...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-15
Journal Detail:
Title:  World journal of urology     Volume:  -     ISSN:  1433-8726     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8307716     Medline TA:  World J Urol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Clinic and Specialistic Sciences-Urology, Polytechnic University of the Marches Region-Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A technical note: pre-operative ultrasound-guided wire localization in head and neck surgery.
Next Document:  Polymerase chain reaction : basic protocols.