| Sacral anterior root stimulated defecation in spinal cord injuries: an experimental study in canine model. | |
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MedLine Citation:
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PMID: 15786558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To investigate whether there was a dominant sacral root for the motive function of rectum and anal sphincter, and to provide an experimental basis for sacral root electrically stimulated defecation in spinal cord injuries. METHODS: Eleven spinal cord injured mongrel dogs were included in the study. After L4-L7 laminectomy, the bilateral L7-S3 roots were electrostimulated separately and rectal and sphincter pressure were recorded synchronously. Four animals were implanted electrodes on bilateral S2 roots. RESULTS: For rectal motorial innervation, S2 was the most dominant (mean 15.2 kPa, 37.7% of total pressure), S1 (11.3 kPa, 27.6%) and S3 (10.9 kPa, 26.7%) contributed to a smaller part. For external anal sphincter, S3 (mean 17.2 kPa, 33.7%) was the most dominant, S2 (16.2 kPa, 31.6%) and S1 (14.3 kPa, 27.9%) contributed to a lesser but still a significant part. Above 85% L7 roots provided some functional contribution to rectum and anal sphincter. For both rectum and sphincter, the right sacral roots provided more contribution than the left roots. Postoperatively, the 4 dogs had electrically stimulated defecation and micturition under the control of the neuroprosthetic device. CONCLUSION: S2 root is the most dominant contributor to rectal pressure in dogs. Stimulation of bilateral S2 with implanted electrodes contributes to good micturition and defecation in dogs. |
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Authors:
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Shi-Min Chang; Guang-Rong Yu; Ying-Min Diao; Meng-Jie Zhang; Shi-Bo Wang; Chun-Lin Hou |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 11 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-03-23 Completed Date: 2005-05-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 1715-8 Citation Subset: IM |
Affiliation:
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Department of Orthopedic Surgery, Tongji Hospital, Tongji University, Shanghai 200065, China. shiminchang@yahoo.com.cn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Defecation* Disease Models, Animal Dogs Electric Stimulation Therapy / methods* Male Pressure Prostheses and Implants* Rectum / innervation, physiology Sacrum Spinal Cord Injuries / therapy* Spinal Nerve Roots / physiology* Urination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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