Document Detail


Sacral anterior root stimulated defecation in spinal cord injuries: an experimental study in canine model.
MedLine Citation:
PMID:  15786558     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To investigate whether there was a dominant sacral root for the motive function of rectum and anal sphincter, and to provide an experimental basis for sacral root electrically stimulated defecation in spinal cord injuries. METHODS: Eleven spinal cord injured mongrel dogs were included in the study. After L4-L7 laminectomy, the bilateral L7-S3 roots were electrostimulated separately and rectal and sphincter pressure were recorded synchronously. Four animals were implanted electrodes on bilateral S2 roots. RESULTS: For rectal motorial innervation, S2 was the most dominant (mean 15.2 kPa, 37.7% of total pressure), S1 (11.3 kPa, 27.6%) and S3 (10.9 kPa, 26.7%) contributed to a smaller part. For external anal sphincter, S3 (mean 17.2 kPa, 33.7%) was the most dominant, S2 (16.2 kPa, 31.6%) and S1 (14.3 kPa, 27.9%) contributed to a lesser but still a significant part. Above 85% L7 roots provided some functional contribution to rectum and anal sphincter. For both rectum and sphincter, the right sacral roots provided more contribution than the left roots. Postoperatively, the 4 dogs had electrically stimulated defecation and micturition under the control of the neuroprosthetic device. CONCLUSION: S2 root is the most dominant contributor to rectal pressure in dogs. Stimulation of bilateral S2 with implanted electrodes contributes to good micturition and defecation in dogs.
Authors:
Shi-Min Chang; Guang-Rong Yu; Ying-Min Diao; Meng-Jie Zhang; Shi-Bo Wang; Chun-Lin Hou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  11     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-23     Completed Date:  2005-05-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1715-8     Citation Subset:  IM    
Affiliation:
Department of Orthopedic Surgery, Tongji Hospital, Tongji University, Shanghai 200065, China. shiminchang@yahoo.com.cn
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MeSH Terms
Descriptor/Qualifier:
Animals
Defecation*
Disease Models, Animal
Dogs
Electric Stimulation Therapy / methods*
Male
Pressure
Prostheses and Implants*
Rectum / innervation,  physiology
Sacrum
Spinal Cord Injuries / therapy*
Spinal Nerve Roots / physiology*
Urination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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