| SYNTAX score is a predictor of angiographic no-reflow in patients with ST-elevation myocardial infarction treated with a primary percutaneous coronary intervention. | |
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MedLine Citation:
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PMID: 23363986 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVES: The no-reflow phenomenon has a negative prognostic value in patients with acute ST-elevation myocardial infarction (STEMI). The SYNTAX score (SS) quantifies the extent and complexity of angiographic disease and predicts long-term mortality and morbidity in STEMI. We aimed to assess the no-reflow and its possible relationships with SS and clinical characteristics in patients with STEMI treated with a primary percutaneous coronary intervention (PPCI). MATERIALS AND METHODS: In this study, 880 patients with STEMI treated with PPCI were included prospectively (646 men and 234 women, mean age 58.5±12.4 years). The SS, thrombolysis in myocardial infarction (TIMI) flow grade score, and TIMI myocardial blush grade score were determined in all patients. No-reflow was defined as TIMI grade 0, 1 and 2 flows or TIMI grade 3 with myocardial blush grade 0 and 1. The patients were divided into two groups: a normal flow group and a no-reflow group. RESULTS: No-reflow was observed in 32.8% of patients. The mean SS of the no-reflow group was higher than that of the normal flow group (19.2±6.8/12.9±6.1, P<0.001). On multivariate logistic regression analysis, SS [β=0.872, 95% confidence interval (CI)=0.845-0.899, P<0.001], diabetes (β=0.767, 95% CI=0.128-4.597, P=0.004), anterior myocardial infarction (β=5.421, 95% CI=1.369-21.469, P=0.025), and thrombus grade after wiring (β=2.537, 95% CI=1.506-4.273, P<0.001) were found to be independent predictors of no-reflow. The cutoff value of SS obtained by the receiver-operator characteristic curve analysis was 19.75 for the prediction of no-reflow (sensitivity: 70.6%, specificity: 69.4%). CONCLUSION: The SS is a predictor of no-reflow in patients with STEMI treated with PPCI. |
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Authors:
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Durmuş Y Sahin; Mustafa Gür; Zafer Elbasan; Osman Kuloğlu; Taner Seker; Ali Kivrak; Ibrahim H Tanboğa; Gökhan Gözübüyük; Sinan Kirim; Murat Cayli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Coronary artery disease Volume: 24 ISSN: 1473-5830 ISO Abbreviation: Coron. Artery Dis. Publication Date: 2013 Mar |
Date Detail:
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Created Date: 2013-01-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9011445 Medline TA: Coron Artery Dis Country: England |
Other Details:
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Languages: eng Pagination: 148-53 Citation Subset: IM |
Affiliation:
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Departments of aCardiology bInternal Medicine, Adana Numune Training and Research Hospital, Adana cDepartment of Cardiology, Faculty of Medicine, Atatürk University, Erzurum, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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