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The SYNTAX Score does not predict presence of carotid disease in a multivessel coronary disease population.
MedLine Citation:
PMID:  24323404     Owner:  NLM     Status:  Publisher    
Background. Numerous reports have shown the relationship between carotid artery atherosclerosis and coronary artery disease (CAD). However, the association between complex CAD evaluated by SYNTAX score (SxScore) and prevalence of carotid lesion has not been fully investigated. We sought to assess the prevalence of carotid atherosclerosis in patients with multivessel CAD assessed by SxScore and the relationship between SxScore severity and features of carotid atherosclerosis. Methods and results. Subjects were 204 consecutive patients with multivessel CAD assessed by coronary angiography and no previous history of carotid atherosclerosis that underwent carotid ultrasound scan (US) from June 2012 to June 2013. Presence of carotid lesion (CL), significant carotid disease (SCD) and carotid plaque morphology was evaluated. At least one CL was found in 159 patients (77.9 %) with no significant difference among SxScore groups (p=0.20 and p=0.54, respectively). High prevalence of complex carotid plaque (CCP) was found without significant different distribution in SxScore groups (p=0.69). Age was independently associated with the presence of CL (odds ratio [OR] 1.055; 95% confidence interval [CI]: 1.015-1.097; p=0.007) and SCD (OR 1.057; 95% CI: 1.008-1.097; p=0.019). Age and diabetes were independently associated with CCP (OR 1.58; 95% CI: 1.023-1.095; p=0.001; OR 1.848; 95% CI: 1.026-3.327; p=0.041). SxScore was not independently associated with carotid lesion, SCD and CCP (all p>0.2). Conclusions. We found high prevalence of CL in patients with multivessel complex CAD. However SxScore does not seem to correlate with carotid atherosclerosis. © 2013 Wiley Periodicals, Inc.
Luca Costanzo; Maria Barbara Campisano; Davide Capodanno; Andrea Sole; Carmelo Grasso; Mario Ragusa; Giuseppe Ronsivalle; Claudia Tamburino; Corrado Tamburino; Luigi Di Pino
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-10
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Wiley Periodicals, Inc., a Wiley company.
Cardiotoracovascular Department, Division of Angiology, Ferrarotto-Policlinic Hospital, University of Catania, Catania, Italy.
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