Document Detail


SUMO changes Sox for developmental diversity.
MedLine Citation:
PMID:  16307912     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The finding that posttranslational modification of the SoxE transcription factors by SUMO regulates specific developmental programs (Taylor and LaBonne [2005], in the journal Developmental Cell) highlights the biological significance of SUMOylation in gene expression and underscores how much there is yet to learn about the function and regulation of this modification.
Authors:
Grace Gill
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular cell     Volume:  20     ISSN:  1097-2765     ISO Abbreviation:  Mol. Cell     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-25     Completed Date:  2006-01-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9802571     Medline TA:  Mol Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  495-6     Citation Subset:  IM    
Affiliation:
Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
DNA-Binding Proteins / metabolism*
High Mobility Group Proteins / metabolism*
Humans
Protein Processing, Post-Translational / physiology*
SOX9 Transcription Factor
SOXE Transcription Factors
SUMO-1 Protein / physiology*
Transcription Factors / metabolism*
Xenopus / embryology,  metabolism
Chemical
Reg. No./Substance:
0/DNA-Binding Proteins; 0/High Mobility Group Proteins; 0/SOX10 protein, human; 0/SOX9 Transcription Factor; 0/SOX9 protein, human; 0/SOXE Transcription Factors; 0/SUMO-1 Protein; 0/Transcription Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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