Document Detail

SUDEP, suspected positional airway obstruction, and hypoventilation in postictal coma.
MedLine Citation:
PMID:  21175606     Owner:  NLM     Status:  MEDLINE    
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of mortality in patients with chronic uncontrolled epilepsy. Despite intense interest in SUDEP from the medical and scientific communities in recent years, its etiologies are still largely unresolved. A 35-year-old woman had SUDEP after having a generalized seizure in the prone position. The cause of her death was likely asphyxia from the convergence of postictal coma and suspected positional airway obstruction and hypoventilation, rather than the commonly suspected periictal cardiac arrhythmia or central apnea. SUDEP may share a similar etiology with sudden infant death syndrome (SIDS) and is likely preventable, at least in a proportion of cases.
James X Tao; Shuo Qian; Maria Baldwin; Xiang-Jun Chen; Sandra Rose; Susan-Hawes Ebersole; John S Ebersole
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-09-24
Journal Detail:
Title:  Epilepsia     Volume:  51     ISSN:  1528-1167     ISO Abbreviation:  Epilepsia     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-23     Completed Date:  2011-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2344-7     Citation Subset:  IM    
Copyright Information:
Wiley Periodicals, Inc. © 2010 International League Against Epilepsy.
Department of Neurology, Adult Epilepsy Center, The University of Chicago, Chicago, IL 60637, USA.
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MeSH Terms
Airway Obstruction / diagnosis*,  etiology,  mortality*
Asphyxia / etiology,  mortality
Cause of Death
Coma / diagnosis*,  etiology,  mortality*
Death, Sudden / epidemiology*,  etiology*
Epilepsy, Tonic-Clonic / diagnosis*,  mortality*
Hypoventilation / diagnosis*,  etiology,  mortality*
Prone Position*
Risk Factors
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