Document Detail


STIM1 and Orai in cardiac hypertrophy and vascular proliferative diseases.
MedLine Citation:
PMID:  23277085     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiac hypertrophy and vascular proliferative diseases are associated with major alterations in calcium homeostasis and calcium signaling. The recent discovery of STIM and Orai has generated great enthusiasm concerning the role of these proteins in the cardiovascular system. We will review the major results concerning the existence and the role of these proteins in the cardiovascular system in normal and pathological situations and their implication in cardiovascular remodeling.
Authors:
Anne-Marie Lompre; Ludovic Benard; Ypuakim Saliba; Fleur Aubart; Jeremy Fauconnier; Jean-Sebastien Hulot
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2013-01-01
Journal Detail:
Title:  Frontiers in bioscience (Scholar edition)     Volume:  5     ISSN:  1945-0524     ISO Abbreviation:  Front Biosci (Schol Ed)     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-01     Completed Date:  2013-09-09     Revised Date:  2014-01-21    
Medline Journal Info:
Nlm Unique ID:  101485241     Medline TA:  Front Biosci (Schol Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  766-73     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / metabolism
Calcium Channels / metabolism*
Calcium Signaling
Cardiomegaly / metabolism*,  pathology
Homeostasis
Humans
Membrane Proteins / metabolism*
Neoplasm Proteins / metabolism*
Grant Support
ID/Acronym/Agency:
R01 HL113497/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Calcium Channels; 0/Membrane Proteins; 0/Neoplasm Proteins; SY7Q814VUP/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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