Document Detail


STAT activation during viral infection in vivo: where's the interferon?
MedLine Citation:
PMID:  20709291     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In this issue of Cell Host & Microbe, O'Gorman et al. (2010) identify a key role for early TLR2-mediated IL-6 production and STAT3 activation in generating protective immunity against poxviruses. These findings highlight the importance of early inflammatory cytokine production in antiviral defense and have implications for enhancing vaccination efficacy.
Authors:
Lionel B Ivashkiv
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell host & microbe     Volume:  8     ISSN:  1934-6069     ISO Abbreviation:  Cell Host Microbe     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-12-14     Revised Date:  2012-05-10    
Medline Journal Info:
Nlm Unique ID:  101302316     Medline TA:  Cell Host Microbe     Country:  United States    
Other Details:
Languages:  eng     Pagination:  132-5     Citation Subset:  -    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA. ivashkivl@hss.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 AI046712-11/AI/NIAID NIH HHS; R01 AI046712-12/AI/NIAID NIH HHS; R01 AI046712-13/AI/NIAID NIH HHS; R01 AI059636-04/AI/NIAID NIH HHS; R01 AR050401/AR/NIAMS NIH HHS; R01 AR050401-06A2/AR/NIAMS NIH HHS; R01 AR050401-07/AR/NIAMS NIH HHS
Comments/Corrections
Comment On:
Cell Host Microbe. 2010 Aug 19;8(2):174-85   [PMID:  20709294 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mammalian PGRPs also mind the fort.
Next Document:  Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut fl...