| ST2 and adrenomedullin in heart failure. | |
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MedLine Citation:
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PMID: 19631176 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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ST2 is the receptor for interleukin-33, a cytokine with antihypertrophic and antifibrotic effects on the myocardium. Serum levels of the soluble form of ST2 serve as a biomarker for ventricular biomechanical strain and provide prognostic information in patients who have symptomatic heart failure. Adrenomedullin is a vasoactive peptide whose actions run counter to the physiologic derangements of clinical heart failure. It appears that measurements of serum adrenomedullin levels can be used to identify those patients who have advanced heart failure and who are at increased risk for heart failure-related death. |
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Authors:
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Rahul Kakkar; Richard T Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Heart failure clinics Volume: 5 ISSN: 1551-7136 ISO Abbreviation: - Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-07-27 Completed Date: 2009-10-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231934 Medline TA: Heart Fail Clin Country: United States |
Other Details:
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Languages: eng Pagination: 515-27 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA. rkakkar@partners.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenomedullin
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physiology* Biological Markers / blood Heart Failure / blood*, diagnosis* Humans Receptors, Cell Surface / blood*, physiology Receptors, Interleukin-1 / blood*, physiology |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/IL1RL1 protein, human; 0/Receptors, Cell Surface; 0/Receptors, Interleukin-1; 148498-78-6/Adrenomedullin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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