| ST-changes in ECG at rest or during exercise indicate a high risk of severe coronary lesions after an episode of unstable coronary artery disease. | |
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MedLine Citation:
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PMID: 8112905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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After an episode of unstable coronary artery disease, 190 patients performed a predischarge exercise test. A postdischarge exercise test and coronary angiography was performed by 172 patients after 1 month. A subgroup of 104 men performed both exercise tests with a computer-aided system. More sophisticated methods of evaluating the ECG reaction during exercise were not diagnostically superior to the simple identification of ST-depression of > or = 0.1 mV. ST-depression in ECG at rest indicated a 70% risk of severe coronary lesions and in such patients, the ECG reaction at exercise carried no additional diagnostic information. Stepwise multiple regression analysis showed that ST-depression and low maximal work load were the most important exercise variables for identification of severe coronary lesions. Using a combination of these parameters, the sensitivity and specificity for identification of severe coronary lesions were, respectively, 77% and 61% predischarge and 77% and 70% after 1 month. |
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Authors:
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J E Karlsson; A Björkholm; E Nylander; J Ohlsson; E Swahn; L Wallentin |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of cardiology Volume: 42 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1994-03-25 Completed Date: 1994-03-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 47-55 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, County Hospital Ryhov, Jönköping, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Angiography Coronary Disease / diagnosis*, drug therapy, epidemiology Double-Blind Method Electrocardiography / methods* Exercise Test Humans Male Middle Aged Regression Analysis Risk Factors Sensitivity and Specificity Signal Processing, Computer-Assisted Tissue Plasminogen Activator / therapeutic use |
| Chemical | |
Reg. No./Substance:
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EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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