| ST-T alternans and myocardial ischemia. | |
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MedLine Citation:
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PMID: 10088801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous studies using intracoronary electrocardiography have demonstrated that ST-T alternans can develop during standard balloon coronary angioplasty. Total occlusion with a large amount of myocardium in jeopardy is the postulated prerequisite. In this study, the authors used perfusion balloons instead of standard balloons, so coronary perfusion was maintained and ischemia was minimized. Fourteen patients with standard balloon technique and 11 patients with perfusion balloon technique were studied. The ST segment was less elevated during perfusion angioplasty (0.15 +/- 0.05 mV vs 1.04 +/- 0.19 mV, p<0.001). There were six (43%) patients with ST-T alternans with standard balloon technique compared with none in the perfusion balloon group (p<0.001). In this study, the authors found that there was less ischemia, less ST segment elevation, and lack of ST-T alternans on the intracoronary electrocardiogram during perfusion balloon angioplasty. These findings support the postulate that a large amount of ischemic myocardium is a prerequisite for ST-T alternans. |
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Authors:
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T Kwan; A Feit; M Alam; E Afflu; L T Clark |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Angiology Volume: 50 ISSN: 0003-3197 ISO Abbreviation: Angiology Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-04-05 Completed Date: 1999-04-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 217-22 Citation Subset: IM |
Affiliation:
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Department of Medicine, State University of New York, Health Science Center at Brooklyn 11203, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angioplasty, Transluminal, Percutaneous Coronary / instrumentation, methods* Anticoagulants / therapeutic use Aspirin / therapeutic use Chi-Square Distribution Coronary Circulation / physiology Coronary Disease / physiopathology, therapy Electrocardiography / classification* Equipment Design Female Heparin / therapeutic use Humans Male Middle Aged Myocardial Ischemia / pathology, physiopathology*, therapy Nitroglycerin / therapeutic use Platelet Aggregation Inhibitors / therapeutic use Time Factors Vasodilator Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Platelet Aggregation Inhibitors; 0/Vasodilator Agents; 50-78-2/Aspirin; 55-63-0/Nitroglycerin; 9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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