| SSRIs & the risk of abnormal bleeding. | |
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MedLine Citation:
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PMID: 17477325 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Considerable research is needed to fully understand the interactions of SSRIs and hematological functioning. Adequate studies of platelet function in patients taking SSRIs are lacking. The risk of bleeding with SSRI treatment appears to be low, and the occurrence of bleeding is usually minor when it does occur. However, the risk does exist and must be considered in any patient taking SSRIs who develops abnormal bleeding or bruising not otherwise explained by an appropriate assessment to determine the etiology. Routine monitoring of patients taking SSRIs should probably include questions about bruising or bleeding, particularly in patients with blood dyscrasias and in older patients taking medications that affect platelet function. Caution should be exercised before starting patients with preexisting bleeding risks on SSRIs, including patients taking NSAIDs, aspirin, or other drugs that may impair coagulation. |
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Authors:
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Roy R Reeves; P Melonee Wise; Sera K Cox |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of psychosocial nursing and mental health services Volume: 45 ISSN: 0279-3695 ISO Abbreviation: J Psychosoc Nurs Ment Health Serv Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-05-04 Completed Date: 2007-05-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200911 Medline TA: J Psychosoc Nurs Ment Health Serv Country: United States |
Other Details:
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Languages: eng Pagination: 15-21 Citation Subset: IM; N |
Affiliation:
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Montgomery VA Medical Center, Jackson, MS 39216, USA. roy.reeves@med.va.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents, Non-Steroidal
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adverse effects Aspirin / adverse effects Case-Control Studies Cohort Studies Databases, Factual Drug Monitoring Drug Synergism Evidence-Based Medicine Fibrinolytic Agents / adverse effects Hemorrhage / chemically induced*, epidemiology, prevention & control Humans Nursing Assessment Population Surveillance Research Design Retrospective Studies Risk Assessment Risk Factors Serotonin Uptake Inhibitors / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Fibrinolytic Agents; 0/Serotonin Uptake Inhibitors; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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