| SS-A (Ro) antibody in random mother-infant pairs. | |
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MedLine Citation:
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PMID: 3871443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a study of the occurrence of detectable antibodies to SS-A and SS-B in 300 randomly selected mother-infant pairs, three (1%) mother-infant pairs were positive for precipitating antibodies to SS-A. No matched pairs were positive for SS-B. Review of the clinical history of the mother-infant pairs with SS-A antibodies failed to reveal evidence of connective tissue disease or the neonatal lupus syndrome. Follow up of two of the three SS-A positive mother-infant pairs two months after delivery also showed no evidence of disease. While the SS-A antibody may be closely associated with the development of the neonatal lupus syndrome, our study does not support the proposed aetiological nature of the antibody. Random maternal screening for possible SS-A antibody positivity and potential neonatal lupus syndrome does not appear to be warranted. |
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Authors:
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M Calmes; B A Bartholomew |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pathology Volume: 38 ISSN: 0021-9746 ISO Abbreviation: J. Clin. Pathol. Publication Date: 1985 Jan |
Date Detail:
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Created Date: 1985-03-05 Completed Date: 1985-03-05 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0376601 Medline TA: J Clin Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 73-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Antinuclear
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analysis* Female Fetal Blood / immunology* Humans Infant, Newborn Lupus Erythematosus, Systemic / immunology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Antinuclear; 0/SS-A antibodies; 0/SS-B antibodies |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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