Document Detail


SPAKling insight into blood pressure regulation.
MedLine Citation:
PMID:  20112249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arterial hypertension is one of the most important health problems in industrialized cities. Blood pressure levels are influenced by renal salt handling and salt reabsorption in the kidney. In this Closeup, Casta?eda-Bueno and Gamba discuss the work from Alessi and coworkers on the in vivo roles of the SPAK kinase in defining blood pressure levels.
Authors:
Mar?a Casta?eda-Bueno; Gerardo Gamba
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  EMBO molecular medicine     Volume:  2     ISSN:  1757-4684     ISO Abbreviation:  EMBO Mol Med     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101487380     Medline TA:  EMBO Mol Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  39-41     Citation Subset:  IM    
Affiliation:
Instituto de Investigaciones Biom?dicas, Universidad Nacional Aut?noma de M?xico.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / physiology*
Homeostasis*
Kidney / physiology
Mice
Models, Biological
Protein-Serine-Threonine Kinases / physiology*
Salts / metabolism
Chemical
Reg. No./Substance:
0/Salts; EC 2.7.1.-/Stk39 protein, mouse; EC 2.7.11.1/Protein-Serine-Threonine Kinases
Comments/Corrections
Comment On:
EMBO Mol Med. 2010 Feb;2(2):63-75   [PMID:  20091762 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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