Document Detail


The SLICC inception cohort for atherosclerosis.
MedLine Citation:
PMID:  18662507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) is a group of rheumatologists and methodologists from 27 international centers who have a particular interest and expertise in systemic lupus erythematosus. Initially, its efforts focused on development and validation of disease activity and damage indices. In 2000, the SLICC Registry for Atherosclerosis was established to determine the incidence, prevalence, nature, and risk factors of atherosclerotic coronary artery disease in systemic lupus erythematosus. Risk factors for coronary artery disease at presentation to the cohort were reported, as well as their accumulation over the first few years. Development of the metabolic syndrome was also described. Among the first 1078 patients who entered the cohort, 61 vascular events have occurred in 47 patients who were older at diagnosis and more likely male and hypertensive than were the patients without vascular events. Additional studies using this cohort are ongoing.
Authors:
Murray B Urowitz; Dafna D Gladman
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Current rheumatology reports     Volume:  10     ISSN:  1534-6307     ISO Abbreviation:  Curr Rheumatol Rep     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-29     Completed Date:  2008-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888970     Medline TA:  Curr Rheumatol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  281-5     Citation Subset:  IM    
Affiliation:
University of Toronto Lupus Clinic, Toronto Western Hospital, Room 1E-409, 399 Bathurst Street, Toronto, ON, Canada. m.urowitz@utoronto.ca
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Atherosclerosis / complications*,  epidemiology
Humans
Incidence
Longitudinal Studies
Lupus Erythematosus, Systemic / complications*
Middle Aged
Prevalence
Registries

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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