Document Detail


SIRT1 Regulation-It Ain't All NAD.
MedLine Citation:
PMID:  22244328     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
SIRT1 is a phylogenetically conserved energy sensor. The molecular mechanisms that regulate its catalytic activity, however, are incompletely understood. Gerhart-Hines et al. (2011) have identified β-adrenergic/cAMP signaling as a regulatory input that rapidly controls SIRT1 activity and fatty acid oxidation.
Authors:
Lily C Chao; Peter Tontonoz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular cell     Volume:  45     ISSN:  1097-4164     ISO Abbreviation:  Mol. Cell     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802571     Medline TA:  Mol Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9-11     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Howard Hughes Medical Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1662, USA; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1662, USA.
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