Document Detail

SIK2 regulates insulin secretion.
MedLine Citation:
PMID:  24576898     Owner:  NLM     Status:  In-Data-Review    
Correct regulation of insulin secretion by the pancreas is crucial for organismal function and survival. The AMPK-related kinase SIK2 (salt-inducible kinase 2) is now shown to be stabilized in pancreatic β-cells following glucose stimulation, leading to improved systemic glucose homeostasis by regulating cellular calcium flux and insulin secretion.
Bengt-Frederik Belgardt; Markus Stoffel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature cell biology     Volume:  16     ISSN:  1476-4679     ISO Abbreviation:  Nat. Cell Biol.     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-02-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890575     Medline TA:  Nat Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  210-2     Citation Subset:  IM    
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