| SBP ratio in exercise stress testing: validation by perfusion imaging. | |
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MedLine Citation:
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PMID: 23328226 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIMS: The 3-min SBP ratio (SBPR) was proposed to detect significant coronary artery disease (CAD), but its relationship with abnormalities detected by myocardial perfusion-gated single-photon emission computed tomography (SPECT) was never examined. METHODS: In 156 consecutive patients submitted to resting and exercise gated SPECT for suspect CAD, perfusion scores, ejection fraction and transient ischemic dilatation (TID) were evaluated and compared with SBPR. RESULTS: There were weak correlations between SBPR and summed stress score (ρ = 0.232, P < 0.004), and summed difference score (SDS) (ρ = 0.228, P < 0.004). According to receiver operating characteristic analysis, SBPR was poorly effective for identifying patients with inducible ischemia (SDS ≥2): area under curve = 0.64, (P < 0.002), sensitivity = 82%, specificity = 40%. No relationship was registered between SBPR and postexercise ejection fraction drop, and the relationship with TID was poor (ρ = 0.263, P < 0.001). CONCLUSION: In patients submitted to gated SPECT for suspect CAD, SBPR appears poorly effective for the detection of significant CAD, and does not show any valuable relationship with exercise-induced functional abnormalities. |
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Authors:
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Matteo Bartolini; Lucia Massi; Leonardo Settimo; Artur Mema; Alberto Pupi; Roberto Sciagrà |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-16 |
Journal Detail:
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Title: Journal of cardiovascular medicine (Hagerstown, Md.) Volume: - ISSN: 1558-2035 ISO Abbreviation: J Cardiovasc Med (Hagerstown) Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101259752 Medline TA: J Cardiovasc Med (Hagerstown) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Nuclear Medicine Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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