Document Detail


The SACD method and the XLRS squamometry tests revisited.
MedLine Citation:
PMID:  18503430     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The assessment of many aspects of the structure and biological dynamics of the stratum corneum can be conducted using calibrated stripping with adhesive-coated discs (SACD). Squamometry entails staining SACD samples with a toluidine blue-basic fuschsin ethanol-based solution and reading the colorimetric variable Chroma C* representing the squamometry index. Four main variants of squamometry index have been designed so far. Squamometry X refers to the assessment of xerosis and any scaly condition. Squamometry L explores the intercorneocyte cohesiveness impaired by ultraviolet light. Squamometry R evaluates stratum corneum renewal and squamometry S assesses the effect of surfactants on corneocyte integrity. This latter variant is related to, although not similar to, the ex-vivo corneosurfametry bioassay. All squamometry tests are rapid, reliable, sensitive and cheap.
Authors:
C Piérard-Franchimont; F Henry; G E Piérard
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cosmetic science     Volume:  22     ISSN:  1468-2494     ISO Abbreviation:  Int J Cosmet Sci     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2008-05-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007161     Medline TA:  Int J Cosmet Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  437-46     Citation Subset:  -    
Affiliation:
Department of Dermatopathology, CHU Sart Tilman, B-4000 Liège, Belgium.
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