Document Detail


S100b Protein Levels in Subretinal Fluid in Rhegmatogenous Retinal Detachment.
MedLine Citation:
PMID:  22671138     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Purpose: To investigate the relevance of the concentration of S100B in subretinal fluid (SRF) with the postoperative anatomical and functional success and proliferative vitreoretinopathy (PVR) formation parameters in rhegmatogenous retinal detachment (RRD). Methods: Fifty-three patients (34 male, 19 female) were included in this prospective study. Study group consisted of 46 patients who had scleral buckling (SB) surgery with the diagnosis of RRD. Control group consisted of six patients who had pars plana vitrectomy (PPV) for either full-thickness macular hole or subluxated intraocular lens. SRFs were obtained during SB surgery. Study cases were divided into three groups, corresponding to the duration of retinal detachment (DRD). Clinical characteristics including best-corrected visual acuity (BCVA), anatomical status at 6 months, the presence of postoperative PVR that resulted in recurrent detachment and any possible re-operations were recorded. The concentration of S100B was quantified by using an enzyme immunoassay test kit. Results: The concentration of S100B in SRF increased significantly after RRD. And, S100B levels were evidently elevated in concordance with DRD. There was no correlation between the concentration of SRF - S100B with preoperative or postoperative BCVA. Again, S100B levels were not related to the extent of RRD or postoperative PVR formation. Conclusion: Concentration of S100B in SRF is good marker of retinal stress and increases in concordance with DRD. However it would not help to predict the possible anatomical and functional success or postoperative PVR formation.
Authors:
Ozgur Yalcinbayir; Rifat Levent Buyukuysal; Berna Akova-Budak; Oner Gelisken
Related Documents :
17979588 - Effects of atomoxetine on growth in children with attention-deficit/hyperactivity disor...
20555008 - Hypoxemia and hypoventilation syndrome improvement after laparoscopic bariatric surgery...
10227908 - Total corporal contouring with megaliposuction (120 consecutive cases).
12828108 - Management delays for early gastric cancer in a country without mass screening.
24155528 - The dual toning technique for melasma treatment with the 1064 nm nd: yag laser: a preli...
19393138 - Unprotected left main intervention: patient selection, operator technique, and clinical...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-6
Journal Detail:
Title:  Current eye research     Volume:  -     ISSN:  1460-2202     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Ophthalmology, Uludag University School of Medicine , Bursa , Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical characteristics and risks of large congenital melanocytic naevi: A review of 31 patients at...
Next Document:  Lichen myco- and photobiont diversity and their relationships at the edge of life (McMurdo Dry Valle...