Document Detail

S100B milk concentration in mammalian species.
MedLine Citation:
PMID:  19482669     Owner:  NLM     Status:  MEDLINE    
S100B is a neurotrophic protein detectable in biological fluids and in human milk. Since there are several maternal-neonatal conditions requiring the administration of animal milks the aim of the present study was to quantify S100B in milk from different mammalian species and to compare protein's concentration among human and mammalian milks. We assessed S100B concentrations in donkey (n=12), goat (n=15) sheep (n=15), commercially available cow (n=8) and human (n=15) milk samples. S100B measurements were performed using an immunoluminometric assay. S100B concentration in human milk (10.41 +/- 4.2 microg/L) was higher (P LESS THAN0.001) than mammalian milks. Of note, S100B concentration in cow milk (3.13 +/- 0.56 microg/L) was higher (P LESS THAN0.01) than that showed in donkey (1.17 +/- 0.26 microg/L), sheep (0.25 +/- 0.11 microg/L) and goat (0.26 +/- 0.11 microg/L). S100B in donkey milk was higher (P LESS THAN0.01) than sheep and goat samples whilst protein's concentration did not differ between goat and sheep. The present study suggests the opportunity of S100B addition to animal milk intended for infant feeding.
Fabio Galvano; Alessandro Frigiola; Luigi Gagliardi; Sabina Ciotti; Matteo Bognanno; Anna Maria Iacopino; Francesco Nigro; Gabriella Lucia Tina; Daniela Cavallaro; Michele Mussap; Andrea Piva; Ester Grilli; Fabrizio Michetti; Diego Gazzolo
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-06-01
Journal Detail:
Title:  Frontiers in bioscience (Elite edition)     Volume:  1     ISSN:  1945-0508     ISO Abbreviation:  Front Biosci (Elite Ed)     Publication Date:  2009  
Date Detail:
Created Date:  2009-06-01     Completed Date:  2010-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485240     Medline TA:  Front Biosci (Elite Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  542-6     Citation Subset:  IM    
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Italy.
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MeSH Terms
Analysis of Variance
Biological Markers / analysis*
Milk / chemistry*
Milk, Human / chemistry*
Nerve Growth Factors / analysis*
S100 Proteins / analysis*
Species Specificity
Reg. No./Substance:
0/Biological Markers; 0/Nerve Growth Factors; 0/S-100 calcium-binding protein beta subunit; 0/S100 Proteins

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