Document Detail


S-100 proteins in the human peripheral nervous system.
MedLine Citation:
PMID:  12645010     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews the distribution of S100 proteins in the human peripheral nervous system. The expression of S100 by peripheral glial cells seems to be a distinctive fact of these cells, independently of their localization and their ability to myelinate or not. S100 proteins expressing cells include satellite cells of sensory, sympathetic and enteric ganglia, supporting cells of the adrenal medulla, myelinating and non-myelinating Schwann cells in the nerve trunks, and the Schwann-related cells of sensory corpuscles. In addition, S100 proteins are expressed in peripheral neurons. Most of them express S100alpha protein, and a subpopulation of sensory neurons in dorsal root ganglia contains S100beta protein or S100alpha plus S100beta proteins.
Authors:
T Gonzalez-Martinez; P Perez-Piñera; B Díaz-Esnal; J A Vega
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Microscopy research and technique     Volume:  60     ISSN:  1059-910X     ISO Abbreviation:  Microsc. Res. Tech.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-03-19     Completed Date:  2003-11-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203012     Medline TA:  Microsc Res Tech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  633-8     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc.
Affiliation:
Departamento de Morfología y Biología Celular, Universidad de 33006 Oviedo, Spain.
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MeSH Terms
Descriptor/Qualifier:
Ganglia / metabolism
Humans
Immunohistochemistry
Neurons / metabolism
Peripheral Nervous System / metabolism*,  pathology
Peripheral Nervous System Neoplasms / metabolism*,  pathology
S100 Proteins / metabolism*
Schwann Cells / metabolism
Chemical
Reg. No./Substance:
0/S100 Proteins

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