| S-100 protein-positive Langerhans cells in various human lung cancers, especially in peripheral adenocarcinomas. | |
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MedLine Citation:
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PMID: 3927583 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The appearance of S-100 protein-positive Langerhans cells was studied in 90 cases of various lung cancers by an immunohistochemical method. S-100 protein-positive dendritic cells were frequently observed in many adenocarcinomas, especially in those subclassified as bronchiolar cell or type II alveolar cell type. However, no S-100 protein-positive cells were found in "goblet cell type" adenocarcinoma. In some cases of squamous cell carcinoma and large cell carcinoma, these dendritic cells were also observed though they were fewer in number. In all cases of small cell carcinoma, however, S-100 protein-positive dendritic cells were rare. Electron microscopic study of two adenocarcinomas clearly demonstrated many Birbeck granules in the cytoplasm of S-100 protein-positive dendritic cells and confirmed that S-100 protein-positive cells in lung cancer were identical with Langerhans cells. |
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Authors:
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T Nakajima; T Kodama; M Tsumuraya; Y Shimosato; T Kameya |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Virchows Archiv. A, Pathological anatomy and histopathology Volume: 407 ISSN: 0174-7398 ISO Abbreviation: Virchows Arch A Pathol Anat Histopathol Publication Date: 1985 |
Date Detail:
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Created Date: 1985-09-25 Completed Date: 1985-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302198 Medline TA: Virchows Arch A Pathol Anat Histopathol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 177-89 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
/
classification,
metabolism*,
pathology Histocytochemistry Humans Immunochemistry Langerhans Cells / metabolism* Lung Neoplasms / classification, metabolism*, pathology Lymphoid Tissue / metabolism, pathology Microscopy, Electron S100 Proteins / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/S100 Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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