Document Detail

Rye, lignans and human health.
MedLine Citation:
PMID:  12749346     Owner:  NLM     Status:  MEDLINE    
Rye bran contains a high content not only of dietary fibre, but also of plant lignans and other bioactive compounds in the so-called dietary fibre complex. Blood concentrations of lignans such as enterolactone have been used as biomarkers of intake of lignan-rich plant food. At present,evidence from studies in human subjects does not warrant the conclusion that rye, whole grains orphyto-oestrogens protect against cancer. Some studies, however, have pointed in that direction,especially in relation to cancers of the upper digestive tract. A number of prospective epidemiological studies have clearly shown a protective effect of wholegrain cereals against myocardial infarctions. A corresponding protective effect against diabetes and ischaemic stroke(brain infarct) has also been demonstrated. It seems reasonable to assume that these protective effects are associated with one or more factors in the dietary fibre complex.
Göran Hallmans; Jie-Xian Zhang; Eva Lundin; Pär Stattin; Anders Johansson; Ingegerd Johansson; Kerstin Hultén; Anna Winkvist; Per Aman; Per Lenner; Herman Adlercreutz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Proceedings of the Nutrition Society     Volume:  62     ISSN:  0029-6651     ISO Abbreviation:  Proc Nutr Soc     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-05-15     Completed Date:  2003-11-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7505881     Medline TA:  Proc Nutr Soc     Country:  England    
Other Details:
Languages:  eng     Pagination:  193-9     Citation Subset:  IM    
Departments of Public Health and Clinical Medicine, University of Umeå, Umeå, Sweden.
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MeSH Terms
Cardiovascular Diseases / diet therapy,  prevention & control*
Diabetes Mellitus, Type 2 / diet therapy,  prevention & control
Dietary Fiber / metabolism*
Health Food
Lignans / metabolism*
Neoplasms / diet therapy,  prevention & control*
Secale cereale / chemistry*
Reg. No./Substance:

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