Document Detail


Ruthenium chloride as an efficient catalytic precursor for hydroarylation reactions via C-H bond activation.
MedLine Citation:
PMID:  20524686     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A very simple and efficient catalytic system for the hydroarylation of olefins by aromatic ketones and Michael acceptors using simple and inexpensive ruthenium trichloride as a ruthenium source is described. These very mild conditions (dioxane at 80 degrees C) appeared to be highly compatible, tolerant, and selective toward various functional groups, and the ease of the protocol is highly convenient for synthetic purposes.
Authors:
Marc-Olivier Simon; Jean-Pierre Genet; Sylvain Darses
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Organic letters     Volume:  12     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-25     Completed Date:  2010-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3038-41     Citation Subset:  IM    
Affiliation:
Laboratoire Charles Friedel (UMR 7223), Ecole Nationale Supérieure de Chimie de Paris, 11 rue P&M Curie, 75231 Paris Cedex 05, France.
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MeSH Terms
Descriptor/Qualifier:
Alkenes / chemistry*
Catalysis
Ketones / chemical synthesis*,  chemistry*
Molecular Structure
Ruthenium Compounds / chemistry*
Stereoisomerism
Chemical
Reg. No./Substance:
0/Alkenes; 0/Ketones; 0/Ruthenium Compounds; 10049-08-8/ruthenium chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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