Document Detail

Ruptured intracranial aneurysms: has the incidence of early rebleeding been over-estimated?
MedLine Citation:
PMID:  7131009     Owner:  NLM     Status:  MEDLINE    
Of 110 consecutive patients with ruptured intracranial aneurysms, 49 underwent delayed neurological deterioration, involving 57 episodes in all. During the first three weeks after the presenting haemorrhage less than a third of these episodes were due to confirmed rebleeding. Rebleeding episodes were found to have a "flat" distribution in time during this period, but episodes of non-haemorrhagic deterioration "peaked" between days 4-12. This peak coincides with the peak for rebleeding which was described in earlier studies on aneurysms, and it is suggested that confusion between non-haemorrhagic deterioration and rebleeding may have led to a significant over-estimate of the incidence of early rebleeding with important implications for the optimum timing of surgical intervention.
R S Maurice-Williams
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  45     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  774-9     Citation Subset:  IM    
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MeSH Terms
Cerebral Angiography
Intracranial Aneurysm / diagnosis*,  mortality,  surgery
Ischemic Attack, Transient / diagnosis
Middle Aged
Rupture, Spontaneous
Subarachnoid Hemorrhage / diagnosis*,  mortality,  surgery
Tomography, X-Ray Computed
Tranexamic Acid / therapeutic use
Reg. No./Substance:
1197-18-8/Tranexamic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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