Document Detail

Ruptured de novo thrombotic giant aneurysm induced by ethyl 2-cyanoacrylate: case report.
MedLine Citation:
PMID:  15451288     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A very rare case of a ruptured aneurysm induced by ethyl 2-cyanoacrylate is reported. CASE DESCRIPTION: Six years earlier, this 68-year-old woman had undergone microvascular decompression for trigeminal neuralgia during which the left vertebral artery, which compressed the exit zone of the trigeminal nerve, had been detached and fixed to the dura mater of the petrous bone with ethyl 2-cyanoacrylate. Shortly thereafter she underwent microvascular decompression for left-side facial palsy; again ethyl 2-cyanoacrylate was used. Six years later, she suffered a subarachnoid hemorrhage because of rupture of a new aneurysm of the left vertebral artery. She was referred to our hospital where coil embolization was attempted on the day following the insult. However, the left vertebral artery and the aneurysm could not be occluded completely, and she suddenly died 20 days later from rerupture of the aneurysm. CONCLUSION: This is the first pathologic report of a ruptured de novo aneurysm induced by ethyl 2-cyanoacrylate. We suggest that arterial wall damage by ethyl 2-cyanoacrylate may have contributed to the development of the de novo aneurysm.
Norio Nakajima; Shinji Nagahiro; Shunji Matsubara; Koichi Satoh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  62     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-28     Completed Date:  2004-10-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  346-51; discussion 351-2     Citation Subset:  IM    
Department of Neurosurgery, School of Medicine, University of Tokushima, Tokushima, Japan.
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MeSH Terms
Aneurysm, Ruptured / chemically induced*,  pathology
Cyanoacrylates / adverse effects*
Hemostatics / adverse effects*
Intracranial Aneurysm / chemically induced*,  pathology
Intracranial Thrombosis / chemically induced*,  pathology
Vertebral Artery / pathology
Reg. No./Substance:
0/Cyanoacrylates; 0/Hemostatics; 7085-85-0/ethyl 2-cyanoacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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