Document Detail

Rupture of a hepatic artery aneurysm caused by Wegener's granulomatosis.
MedLine Citation:
PMID:  9112274     Owner:  NLM     Status:  MEDLINE    
Among vasculitis syndromes Wegener's granulomatosis (WG) is characterized by involvement of the upper and lower airways and kidneys. The associated vasculitis involves small and medium sized arteries and veins. Aneurysm formation and a segmental pattern of involvement of larger arteries is not typically seen in WG--a presentation more in keeping with polyarteritis nodosa. We report on a patient hospitalized with classical manifestations of WG who died suddenly of hypovolemic shock caused by intraperitoneal hemorrhage resulting from rupture of a hepatic artery aneurysm. The aneurysm was caused by involvement of the hepatic artery in the disease process. To our knowledge aneurysmatic dilatation of the hepatic artery due to WG has not been previously described. This case illustrates an unusual disease course in WG and the overlap which exists in classical vasculitis syndromes.
M A den Bakker; P L Tangkau; T W Steffens; S L Tjiam; E M van der Loo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology, research and practice     Volume:  193     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1997  
Date Detail:
Created Date:  1997-06-12     Completed Date:  1997-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  61-6     Citation Subset:  IM    
Dept. of Pathology, Reinier de Graaf Gasthuis/Diagnostisch centrum SSDZ, Delft.
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MeSH Terms
Aneurysm, Ruptured / etiology*,  pathology,  ultrasonography
Fatal Outcome
Hepatic Artery*
Middle Aged
Shock / etiology,  pathology
Wegener Granulomatosis / complications*,  pathology

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