Document Detail

Rupture of ectopic pregnancy with minimally detectable beta-human chorionic gonadotropin levels: a report of 2 cases.
MedLine Citation:
PMID:  17694977     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Several studies have demonstrated that 25-77% of ectopic pregnancies spontaneously resolve with expectant management. However, expectant management is controversial and should be considered only for patients with small, unruptured gestational sacs, low beta-human chorionic gonadotropin (beta-hCG) levels and absence of symptoms. There is no consensus on how long to follow such patients. CASES: Two patients with beta-hCG levels < 10 mIU/mL presented with ruptured ectopic pregnancy and hemoperitoneum. CONCLUSION: While expectant management of a suspected ectopic pregnancy may allow spontaneous resolution of such an ectopic pregnancy, rupture may occur at any time and even with extremely low beta-hCG levels. Patients need to be counseled about the risks of rupture and symptoms, immediate action should be taken if symptoms develop, and serum beta-hCG levels should be followed to zero.
Joyce Fu; Melinda B Henne; Sylvie Blumstein; Ruth B Lathi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  52     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-08-14     Completed Date:  2007-09-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  541-2     Citation Subset:  IM    
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Stanford University IVF Program, 900 Welch Road, Suite 350, Palo Alto, CA 94304, USA.
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MeSH Terms
Chorionic Gonadotropin, beta Subunit, Human / blood*,  metabolism
Hemoperitoneum / etiology*
Pregnancy, Ectopic / pathology*
Rupture, Spontaneous
Reg. No./Substance:
0/Chorionic Gonadotropin, beta Subunit, Human

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