| Rupture of the arterial wall causes deflection in pressure time course during ex vivo balloon angioplasty. | |
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MedLine Citation:
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PMID: 9286552 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A relation between restenosis and arterial lesions resulting from balloon angioplasty has been suggested in literature. Nevertheless, it is unclear to what extent angioplasty-induced arterial wall lesions contribute to the occurrence of restenosis. One problem is that arterial ruptures cannot be detected during balloon inflation. This study describes a method to detect ruptures in the arterial wall, based on deflections observable in the development of the balloon pressure. We performed ex vivo angioplasty with constant strain rate on 28 human femoral artery segments, showing deflections in 21 cases. In 20 cases wall rupture was confirmed histologically. From seven cases not showing deflections, four showed intact wall at microscopy. These figures result in a selectivity of the proposed method of 87 +/- 7% and a predictive value of the positive test of 95 +/- 5%. We conclude that this method can enhance detection of arterial rupture during ex vivo angioplasty and may become important clinically. |
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Authors:
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J L Steenhuijsen; S R Vaartjes; C J Poortermans; M G Havenith; H B Boom |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Catheterization and cardiovascular diagnosis Volume: 42 ISSN: 0098-6569 ISO Abbreviation: Cathet Cardiovasc Diagn Publication Date: 1997 Sep |
Date Detail:
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Created Date: 1997-10-23 Completed Date: 1997-10-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7508512 Medline TA: Cathet Cardiovasc Diagn Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 92-101 Citation Subset: IM |
Affiliation:
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Department of Electrical Engineering, University Twente, Enschede, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angioplasty, Balloon* Cadaver Constriction, Pathologic Elasticity Femoral Artery / pathology* Humans Predictive Value of Tests Pressure Recurrence Rupture |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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