| [Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components. | |
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MedLine Citation:
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PMID: 19926139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The 'molecular light switch' complexes [Ru(bpy)(2)(dppz)](2+) (1) and [Ru(phen)(2)(dppz)](2+) (2), where bpy=2,2'-bipyridine, phen=1,10-phenanthroline and dppz=dipyrido[3,2-a:2',3'-c]phenazine, have been explored as probes for diagnosing and staining nuclear components. The phen complex acts as a better staining agent for nonviable cells than for viable cells and exhibits a staining efficiency in tail region of comet more specific and stronger than the already known dye Hoechst 33258. |
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Authors:
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Venugopal Rajendiran; Mallayan Palaniandavar; Vaiyapuri Subbarayan Periasamy; Mohammad Abdulkader Akbarsha |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-10-23 |
Journal Detail:
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Title: Journal of inorganic biochemistry Volume: 104 ISSN: 1873-3344 ISO Abbreviation: J. Inorg. Biochem. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905788 Medline TA: J Inorg Biochem Country: United States |
Other Details:
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Languages: eng Pagination: 217-20 Citation Subset: IM |
Affiliation:
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Centre for Bioinorganic Chemistry, School of Chemistry, Bharathidasan University, Tiruchirapalli 620 024, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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2,2'-Dipyridyl
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chemistry* Animals Bisbenzimidazole / chemistry Cell Line, Tumor Cell Nucleus / chemistry* Cell Survival / drug effects Humans Inhibitory Concentration 50 Lymphocytes / chemistry, cytology Male Microscopy, Fluorescence Nucleic Acids / chemistry Phenanthrolines / chemistry* Rats Rats, Wistar Ruthenium Compounds / chemistry*, pharmacology Spermatozoa / chemistry, cytology Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids; 0/Phenanthrolines; 0/Ruthenium Compounds; 23491-44-3/Bisbenzimidazole; 366-18-7/2,2'-Dipyridyl; 66-71-7/1,10-phenanthroline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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