| Run-up to participation in ATACH II in Japan. | |
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MedLine Citation:
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PMID: 23230457 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Intracerebral hemorrhage (ICH) is a major cause of morbidity and mortality in Japan. Seventeen Japanese institutions are participating in the Antihypertensive Treatment for Acute Cerebral Hemorrhage (ATACH) II Trial (ClinicalTrials.gov no. NCT01176565; UMIN 000006526). This phase III trial is designed to determine the therapeutic benefit of early intensive systolic blood pressure (BP) lowering for acute hypertension in ICH patients. This report explains the long run-up to reach the start of patient registration in ATACH II in Japan, including our preliminary study, a nationwide survey on antihypertensive treatment for acute ICH patients, a multicenter study for hyperacute BP lowering (the SAMURAI-ICH study), revision of the official Japanese label for intravenous nicardipine, and construction of the infrastructure for the trial. |
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Authors:
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K Toyoda; S Sato; M Koga; H Yamamoto; J Nakagawara; E Furui; Y Shiokawa; Y Hasegawa; S Okuda; N Sakai; K Kimura; Y Okada; S Yoshimura; H Hoshino; Y Uesaka; T Nakashima; Y Itoh; T Ueda; T Nishi; J Gotoh; K Nagatsuka; S Arihiro; T Yamaguchi; K Minematsu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of vascular and interventional neurology Volume: 5 ISSN: 1941-5893 ISO Abbreviation: J Vasc Interv Neurol Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-12-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101511381 Medline TA: J Vasc Interv Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 1-5 Citation Subset: - |
Affiliation:
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Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita 565-8565, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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