| Royal Jelly Protects Against Ultraviolet B-Induced Photoaging in Human Skin Fibroblasts via Enhancing Collagen Production. | |
| | |
MedLine Citation:
|
PMID: 21812645 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract Royal jelly (RJ) is a honeybee product containing proteins, carbohydrates, fats, free amino acids, vitamins, and minerals. As its principal unsaturated fatty acid, RJ contains 10-hydroxy-2-decenoic acid (10-HDA), which may have antitumor and antibacterial activity and a capacity to stimulate collagen production. RJ has attracted interest in various parts of the world for its pharmacological properties. However, the effects of RJ on ultraviolet (UV)-induced photoaging of the skin have not been reported. In this study we measured the 10-HDA content of RJ by high-performance liquid chromatography and tested the effects of RJ on UVB-induced skin photoaging in normal human dermal fibroblasts. The effects of RJ and 10-HDA on UVB-induced photoaging were tested by measuring procollagen type I, transforming growth factor (TGF)-β1, and matrix metalloproteinase (MMP)-1 after UVB irradiation. The RJ contained about 0.211% 10-HDA. The UVB-irradiated human skin fibroblasts treated with RJ and 10-HDA had increased procollagen type I and TGF-β1 productions, but the level of MMP-1 was not changed. Thus RJ may potentially protect the skin from UVB-induced photoaging by enhancing collagen production. |
| | |
Authors:
|
Hye Min Park; Eunson Hwang; Kwang Gill Lee; Sang-Mi Han; Yunhi Cho; Sun Yeou Kim |
Related Documents
:
|
4041855 - A metabolic profile of the rat caudate microvasculature: a histochemical study. 6774935 - Isolation, characterization and biological activities of verotetrone from a mutant stra... 10081985 - Southeast asian ovalocytosis in white persons. 7120085 - Effects of 3-chloromethylthiochromone-1,1-dioxide on nucleic acid, protein, and aerobic... 18568445 - Morphology of immature stages of hemipyrellia ligurriens (wiedemann) (diptera: callipho... 12729835 - In vitro cytotoxicity to human cells in culture of some phenolics from olive oil. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-8-3 |
Journal Detail:
|
Title: Journal of medicinal food Volume: - ISSN: 1557-7600 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
|
Created Date: 2011-8-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9812512 Medline TA: J Med Food Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1 Department of Medical Science, Kyung Hee University , Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of Oolong Tea on Gene Expression of Gluconeogenic Enzymes in the Mouse Liver and in Rat Hepa...
Next Document: Antioxidant and Anticarcinogenic Effects of Methanolic Extract and Volatile Oil of Fennel Seeds (Foe...