| Routine thyroid function tests as a case-finding tool. | |
| | |
MedLine Citation:
|
PMID: 2609654 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A comprehensive, multiphasic blood panel was used as a case-finding tool for 738 patients. The thyroid function tests T4 (total thyroxine), rT3U (resin T3 uptake), and FTI (free thyroxine index) were included in this panel. Among the 711 patients found to be clinically euthyroid without known thyroid disorder, 54 had at least one abnormal parameter. Of these patients, four new diagnoses of thyroid dysfunction were made. All four cases had an abnormal T4 and FTI. Two patients had a slightly elevated FTI and normal T4, and have remained clinically euthyroid. All other patients had a normal FTI, and no thyroid dysfunction was noted. This gives FTI in this study a sensitivity of 1.0 and specificity of 0.993, which is camparable to what others have found (1). The prevalence of unsuspected thyroid dysfunction was 0.56 per cent, again comparable to other studies (1-3). It would seem the high sensitivity/specificity of FTI offsets the relatively low prevalence of unsuspected thyroid dysfunction. Since FTI is a sensitive predictor of thyroid dysfunction, consideration should be given to the inclusion of thyroid function studies in existing multiphasic case-finding panels. |
| | |
Authors:
|
J V Ashley |
Related Documents
:
|
6302494 - Autoimmunity in the lambert-eaton myasthenic syndrome. 7647404 - Ten-year follow-up study of thyroid function in euthyroid patients with simple goiter o... 10090314 - Increased serum concentration of interleukin-12 in patients with silent thyroiditis and... 2855724 - Spectrum of thyroid function abnormalities in gestational trophoblastic neoplasia. 20124994 - Perioperative considerations in patients with cirrhotic cardiomyopathy. 6932954 - The association of eosinophilia with lymphoblastic leukaemia or lymphoma: a study of se... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The West Virginia medical journal Volume: 85 ISSN: 0043-3284 ISO Abbreviation: W V Med J Publication Date: 1989 Oct |
Date Detail:
|
Created Date: 1990-02-22 Completed Date: 1990-02-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0413777 Medline TA: W V Med J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 425-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Family Practice Female Humans Male Thyroid Diseases / diagnosis Thyroid Function Tests* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lassa and Mozambique viruses: cross protection in experiments on mice and action of immunosuppressan...
Next Document: Smoke inhalation.