Document Detail


Routine thyroid function tests as a case-finding tool.
MedLine Citation:
PMID:  2609654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A comprehensive, multiphasic blood panel was used as a case-finding tool for 738 patients. The thyroid function tests T4 (total thyroxine), rT3U (resin T3 uptake), and FTI (free thyroxine index) were included in this panel. Among the 711 patients found to be clinically euthyroid without known thyroid disorder, 54 had at least one abnormal parameter. Of these patients, four new diagnoses of thyroid dysfunction were made. All four cases had an abnormal T4 and FTI. Two patients had a slightly elevated FTI and normal T4, and have remained clinically euthyroid. All other patients had a normal FTI, and no thyroid dysfunction was noted. This gives FTI in this study a sensitivity of 1.0 and specificity of 0.993, which is camparable to what others have found (1). The prevalence of unsuspected thyroid dysfunction was 0.56 per cent, again comparable to other studies (1-3). It would seem the high sensitivity/specificity of FTI offsets the relatively low prevalence of unsuspected thyroid dysfunction. Since FTI is a sensitive predictor of thyroid dysfunction, consideration should be given to the inclusion of thyroid function studies in existing multiphasic case-finding panels.
Authors:
J V Ashley
Related Documents :
6302494 - Autoimmunity in the lambert-eaton myasthenic syndrome.
7647404 - Ten-year follow-up study of thyroid function in euthyroid patients with simple goiter o...
10090314 - Increased serum concentration of interleukin-12 in patients with silent thyroiditis and...
24517504 - The distribution of hla-b27 subtype distribution in patients with ankylosing spondyliti...
20124994 - Perioperative considerations in patients with cirrhotic cardiomyopathy.
6932954 - The association of eosinophilia with lymphoblastic leukaemia or lymphoma: a study of se...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The West Virginia medical journal     Volume:  85     ISSN:  0043-3284     ISO Abbreviation:  W V Med J     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1990-02-22     Completed Date:  1990-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0413777     Medline TA:  W V Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  425-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Family Practice
Female
Humans
Male
Thyroid Diseases / diagnosis
Thyroid Function Tests*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Lassa and Mozambique viruses: cross protection in experiments on mice and action of immunosuppressan...
Next Document:  Smoke inhalation.