Document Detail


Routine scrotal ultrasonography during the follow-up of patients with testicular cancer leads to earlier detection of asynchronous tumours and a high rate of organ preservation.
MedLine Citation:
PMID:  19793379     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To compare outcomes of patients with asynchronous tumours detected before and after the introduction of scrotal ultrasonography (SUS) during routine follow-up examinations.
PATIENTS AND METHODS: Since January 2001 SUS was also used during the follow-up of patients with testicular cancer. A series of 16 consecutive patients with asynchronous bilateral testicular tumours diagnosed while still complying with routine follow up investigations were identified and divided into two groups; group A was diagnosed by palpation only, before 2001, and group B was diagnosed after 2000. The groups were compared statistically for the interval between asynchronous tumours, clinical stage, tumour diameter at the time of diagnosis and rate of testis-sparing surgery.
RESULTS: All tumours in group A were diagnosed by palpation, but only two in group B were palpable at the time of diagnosis. The mean tumour diameter was statistically significantly smaller in group B (1.2 cm) than in group A (2.68 cm); testis-sparing surgery was used in all of group B and only three patients in group A. After organ-sparing surgery all patients had normal testosterone levels. All patients after organ-sparing surgery had adjuvant scrotal radiotherapy because of germ cell tumour, and no patient had a local recurrence.
CONCLUSION: Our data indicate that using SUS for the remaining testicle in routine follow-up visits of patients with testicular cancer leads to the earlier detection of smaller tumours and, consequently, a higher rate of organ preservation. The maintenance of physiological endocrine function might finally result in a better quality of life.
Authors:
Brigitte Stoehr; Florian Zangerl; Eberhard Steiner; Nicolai Leonhartsberger; Andreas Fritzer; Georg Bartsch; Hannes Steiner
Related Documents :
18796519 - Selective use of bilateral inferior petrosal sinus sampling in patients with adrenocort...
12519419 - Recombinant human growth hormone treatment in elderly patients undergoing elective tota...
24002759 - The volume effect in liver surgery-a systematic review and meta-analysis.
19156519 - Variation in colonoscopic technique and adenoma detection rates at an academic gastroen...
11124859 - Markers of tumor invasion are major predictive factors for the long-term outcome of cor...
22959569 - Reoperative sternotomy is associated with increased mortality after heart transplantation.
19592389 - Development and validation of a clinical index to predict survival after cardiac resync...
23816939 - Preoperative acetazolamide spect is useful for predicting outcome of shunt operation in...
7791169 - Protective effect of misoprostol on indomethacin induced renal dysfunction in elderly p...
Publication Detail:
Type:  Journal Article     Date:  2009-09-29
Journal Detail:
Title:  BJU international     Volume:  105     ISSN:  1464-410X     ISO Abbreviation:  BJU Int.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2012-01-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  1118-20     Citation Subset:  IM    
Copyright Information:
© 2009 THE AUTHORS. JOURNAL COMPILATION © 2009 BJU INTERNATIONAL.
Affiliation:
Urology, Medical University Innsbruck, Innsbruck, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of the dual 5alpha-reductase inhibitor, dutasteride, on serum testosterone and body mass inde...
Next Document:  Biomarkers in bladder cancer.