| Routine positron emission tomography and positron emission tomography/computed tomography in melanoma staging with positive sentinel node biopsy is of limited benefit. | |
| | |
MedLine Citation:
|
PMID: 18227709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Positron emission tomography (PET) is increasingly used for the staging and management of melanoma. The aim of this study was to evaluate the role of PET or PET/ computed tomography (CT) as a routine procedure in patients with positive sentinel node biopsy (SNB). Thirty patients with melanoma of Breslow thickness greater than 1 mm who had PET or PET/CT scans performed within 100 days after a positive SNB were reviewed retrospectively. Two patients (6%) had a positive PET scan, none of which were melanoma related. The first patient had a synchronous neuroendocrine thyroid tumour and the second patient had increased uptake in the chest wall, which proved to be old trauma. Lymph node dissection was positive in five cases (16%). With a median follow-up of 24 months, 21 patients remained disease free. In none of the 30 cases did the early PET scan after a positive SNB alter subsequent melanoma management. The role of PET scanning soon after a positive sentinel node biopsy seems to be of limited benefit. It is questionable whether any imaging is beneficial at this stage. The results of this review suggest that PET scanning might not be indicated for this group of patients. |
| | |
Authors:
|
Anastasia Constantinidou; Michael Hofman; Michael O'Doherty; Katharine M Acland; Ciaran Healy; Mark Harries |
Related Documents
:
|
14645979 - Metabolic significance of the pattern, intensity and kinetics of 18f-fdg uptake in mali... 17180659 - Integrated pet/ct as a first-line re-staging modality in patients with suspected recurr... 18716509 - Pet/ct in the evaluation of lymphoma in patients with hiv-1 with suppressed viral loads. 11973489 - Reproducibility and clinical value of 18f-fluorodeoxyglucose positron emission tomograp... 12228759 - Positron emission tomography in urologic oncology. 19692289 - Advances in imaging in the work-up of head and neck cancer patients. 21885719 - Extratemporal damage in temporal lobe epilepsy: magnetization transfer adds information... 8254049 - Entry of cholera toxin into polarized human intestinal epithelial cells. identification... 12200249 - Appendicitis: spectrum of appearances on helical ct. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Melanoma research Volume: 18 ISSN: 0960-8931 ISO Abbreviation: Melanoma Res. Publication Date: 2008 Feb |
Date Detail:
|
Created Date: 2008-01-29 Completed Date: 2008-04-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9109623 Medline TA: Melanoma Res Country: England |
Other Details:
|
Languages: eng Pagination: 56-60 Citation Subset: IM |
Affiliation:
|
Melanoma Unit, Guy's and St Thomas' Foundation NHS Trust, London, UK. a.constantinidou@yahoo.co.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Female Follow-Up Studies Humans Male Melanoma / pathology, radiography*, radionuclide imaging* Middle Aged Neoplasm Recurrence, Local / diagnosis Neoplasm Staging Neuroendocrine Tumors / etiology, pathology Positron-Emission Tomography / methods* Retrospective Studies Sentinel Lymph Node Biopsy* Skin Neoplasms / pathology, radiography*, radionuclide imaging* Thoracic Wall / pathology Thyroid Neoplasms / etiology, pathology Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ganglioside signatures of primary and nodal metastatic melanoma cell lines from the same patient.
Next Document: Evidence and interdisciplinary consensus-based German guidelines: surgical treatment and radiotherap...