| Routine intracranial pressure monitoring in acute coma. | |
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MedLine Citation:
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PMID: 20166062 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Studies in traumatic encephalopathy first led to the insight that the damage seen was not just due to direct consequences of the primary injury. A significant, and potentially preventable, contribution to the overall morbidity arose from secondary hypoxic-ischaemic damage. Brain swelling accompanied by raised intracranial pressure (ICP) resulted in inadequate cerebral perfusion with well-oxygenated blood. Detection of raised ICP could be useful in alerting clinicians to the need to improve cerebral perfusion, with consequent reductions in brain injury. OBJECTIVES: To determine whether routine ICP monitoring in all acute cases of severe coma reduces the risk of all-cause mortality or severe disability at final follow-up. SEARCH STRATEGY: We searched the Cochrane Injuries Group's Specialised Register (searched 7 April 2009), CENTRAL (The Cochrane Library 2009, Issue 1), MEDLINE 1950 to March week 4 2009, EMBASE 1980 to week 14 March 2009, CINAHL 1982 to March 2009, ISI Web of Science: Science Citation Index Expanded (SCI-EXPANDED) 1970 to March 2009, Conference Proceedings Citation Index- Science (CPCI-S) 1990 to March 2009, PubMed (searched 7 April 2009, limit; added in last 6 months). The searches were last updated in April 2009. SELECTION CRITERIA: All randomised controlled studies of real-time ICP monitoring by invasive or semi-invasive means in acute coma (traumatic or non-traumatic aetiology) versus no ICP monitoring (that is, clinical assessment of ICP). DATA COLLECTION AND ANALYSIS: Primary outcome measures were all-cause mortality and severe disability at the end of the follow-up period. MAIN RESULTS: No studies meeting the selection criteria have been identified to date. AUTHORS' CONCLUSIONS: There are no data from randomised controlled trials that can clarify the role of ICP monitoring in acute coma. |
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Authors:
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Rob J Forsyth; Susanne Wolny; Beryl Rodrigues |
Publication Detail:
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Type: Journal Article; Review Date: 2010-02-17 |
Journal Detail:
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Title: Cochrane database of systematic reviews (Online) Volume: - ISSN: 1469-493X ISO Abbreviation: Cochrane Database Syst Rev Publication Date: 2010 |
Date Detail:
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Created Date: 2010-02-18 Completed Date: 2010-04-19 Revised Date: 2010-10-21 |
Medline Journal Info:
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Nlm Unique ID: 100909747 Medline TA: Cochrane Database Syst Rev Country: England |
Other Details:
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Languages: eng Pagination: CD002043 Citation Subset: IM |
Affiliation:
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Institute of Neuroscience, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne, Tyne & Wear, UK, NE1 4LP. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Brain Injuries / complications Cerebrovascular Circulation* Coma / physiopathology* Humans Intracranial Hypertension / physiopathology* Intracranial Pressure / physiology Monitoring, Physiologic / methods |
| Comments/Corrections | |
Update Of:
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Cochrane Database Syst Rev. 2001;(3):CD002043
[PMID:
11687010
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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