| Routine cervical cerclage in higher order multiple gestation -- does it prolong the pregnancy? | |
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MedLine Citation:
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PMID: 11931683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preterm birth following cervical dilatation is the greatest threat to infants of a multiple pregnancy. Lacking reliable data concerning the effect of prophylactic cerclage, we compared a study group to controls for maternal and perinatal outcome. Sixteen of 94 triplet-, 9 of 18 quadruplet/quintuplet-pregnancies, treated with prophylactic cerclage, were retrospectively compared to those without cervical cerclage respectively. Kruskal-Wallis test and Mann-Whitney-U test were performed as non-parametric one way analysis of variance. For the analysis of frequencies Chi Square test or Fisher's exact test were performed. Odds ratio with 95% confidence interval was used to compare the need for intravenous tocolysis as well as perinatal morbidity and mortality. Gestational age at delivery was not different from the controls in all studied groups. Birth weight revealed a 200 g dominance for the "no cerclage-triplets", while this significant difference was inverted for quadruplets/quintuplets (1245 g vs. 1069 g). With respect to gestational age at birth, need for hospitalisation or medical intervention no benefit was achieved. Moreover, perinatal outcome analysed by arterial pH, APGAR-Score and perinatal mortality was not altered by a prophylactic cerclage. Perinatal morbidity for quadruplets and quintuplets was even higher in cerclage pregnancies. Therefore, these retrospective results disclaim a positive impact of cervical cerclage on pregnancy management or perinatal outcome in multifetal pregnancies. |
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Authors:
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Alexander Strauss; Ivo M Heer; Udo Janssen; Christian Dannecker; Peter Hillemanns; Susanne Müller-Egloff |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Twin research : the official journal of the International Society for Twin Studies Volume: 5 ISSN: 1369-0523 ISO Abbreviation: Twin Res Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-04-04 Completed Date: 2002-08-15 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9815819 Medline TA: Twin Res Country: Australia |
Other Details:
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Languages: eng Pagination: 67-70 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology - Grosshadern, University of Munich, Germany. Alexander.Strauss@helios.med.uni-muechen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Apgar Score Cerclage, Cervical* Female Gestational Age Humans Infant Infant Mortality Infant, Low Birth Weight Infant, Newborn Obstetric Labor, Premature / prevention & control* Odds Ratio Pregnancy Pregnancy Outcome Pregnancy, Multiple* / physiology Quadruplets Quintuplets Retrospective Studies Triplets |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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