| Routine postoperative administration of vitamin D and calcium after total thyroidectomy: a meta-analysis. | |
MedLine Citation:
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PMID: 20804871 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Temporary hypocalcemia is a frequent complication after total thyroidectomy. Routine postoperative administration of vitamin D and calcium can reduce the incidence of symptomatic postoperative hypocalcemia. We undertook a systematic review to assess the effectiveness of this intervention. METHODS: We identified randomized controlled trials comparing the administration of vitamin D or metabolites to oral calcium or no treatment in patients after total thyroidectomy in MEDLINE, EMBASE and LILACS databases. RESULTS: Four studies with 706 patients were included: 346 in the calcitriol group, 288 in the oral calcium group and 72 in the control group. The rates of hypocalcemia symptoms were 4%, 19% and 31%, respectively. The OR value for the comparison between calcitriol + calcium as compared to no treatment and to exclusive calcium treatment groups was 0.32 (95% CI, 0.13-0.79) and 0.31 (95% CI, 0.14-0.70), respectively. CONCLUSION: The prophylactic treatment with vitamin D or metabolites + calcium is effective to decrease the incidence of symptoms of temporary hypocalcemia. |
Authors:
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Alvaro Sanabria; Luis C Dominguez; Valentin Vega; Camilo Osorio; Daniel Duarte |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-08 |
Journal Detail:
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Title: International journal of surgery (London, England) Volume: 9 ISSN: 1743-9159 ISO Abbreviation: Int J Surg Publication Date: 2011 |
Date Detail:
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Created Date: 2011-01-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101228232 Medline TA: Int J Surg Country: England |
Other Details:
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Languages: eng Pagination: 46-51 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Surgery, School of Medicine, Universidad de La Sabana, Bogota, Campus Puente del Comun, Km 21 Autopista Norte, Chia, Colombia. alvarosanabria@gmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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