Document Detail

Routine CMV screening during pregnancy.
MedLine Citation:
PMID:  15099862     Owner:  NLM     Status:  MEDLINE    
Cytomegalovirus (CMV) screening during pregnancy has been widely discussed for several years, but still no consensus has been agreed. With a number of live births of 750,000 per year in France, we would expect 7500 infected infants at birth per year (rate of congenital infection of 1%). Among infected infants at birth, the number of severely infected foetuses would be approximately 75, the number of infants with severe sequelae would be 480, 675 approximately would present with hearing loss and the number of asymptomatic infants would be 6270. Five different preventive methods for congenital CMV infection are possible: (1) Routine CMV screening at the beginning of pregnancy for primary prevention. (2) Secondary prevention by antenatal diagnosis of congenital CMV infection complications. (3) Tertiary prevention by serological testing during pregnancy. (4) Tertiary prevention by serological screening at birth. (5) Tertiary prevention: Hearing loss screening at birth. The aims of this review are to define the advantages and disadvantages of these different methods of CMV screening during pregnancy and to determine if the current available information would make systematic testing acceptable.
P Collinet; D Subtil; V Houfflin-Debarge; N Kacet; A Dewilde; F Puech
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  114     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-04-21     Completed Date:  2004-08-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  3-11     Citation Subset:  IM    
Clinique de Gynécologie, Hôpital Jeanne de Flandre, Obstétrique et Néonatalogie, Centre Hospitalier Régional Universitaire de Lille, 59037 Lille Cedex, France.
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MeSH Terms
Cytomegalovirus Infections / congenital,  epidemiology,  prevention & control*
France / epidemiology
Infant, Newborn
Mass Screening
Neonatal Screening
Pregnancy Complications, Infectious / epidemiology,  prevention & control*
Prenatal Diagnosis*

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