Document Detail

Route-specific daily uptake of organochlorine pesticides in food, dust, and air by Shanghai residents, China.
MedLine Citation:
PMID:  23063733     Owner:  NLM     Status:  Publisher    
Dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexanes (HCHs) are widely detected in the environment, although they have been banned in China since 1980s. To better understand the route-specific daily uptake of the pesticides by humans, a total of 322 food, dust, and air samples were collected in Shanghai, China, during 2008-2011. The median concentrations were 0.2-126.6 and 0.03-1.6ng/g wet weight for DDTs (DDT and its metabolites) and HCHs, respectively, in different types of foods. The values in dust (indoors and outdoors) were 5.7-29.8 and 1.3-5.4ng/g, and 13.9×10(-3) and 2.6×10(-3)ng/m(3) in air (gas+particle) for DDTs and HCHs, respectively. The daily uptake of a pesticide by humans was calculated via the pesticide intake multiplied by its uptake efficiency. The uptake efficiencies of DDTs and HCHs in food through human intestines were estimated using bioaccessibility measured via an in vitro method simulating the human gastrointestinal digestion process. The total daily uptakes of DDTs and HCHs through three routes (i.e., ingestion, inhalation, and dermal contact) were 79.4 and 4.9ng/day, respectively, for children, and 131.1 and 8.0ng/day, respectively, for adults. Ingestion via food and dust was the main route of human exposure to the pesticides, and the daily uptake of the pesticides via food consumption accounted for 95.0-99.2% of the total.
Yingxin Yu; Chunlei Li; Xiaolan Zhang; Xinyu Zhang; Yuping Pang; Shaohuan Zhang; Jiamo Fu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-9
Journal Detail:
Title:  Environment international     Volume:  50C     ISSN:  1873-6750     ISO Abbreviation:  Environ Int     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  31-37     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR China. Electronic address:
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