Document Detail


Rous sarcoma virus genome stably integrated into mouse ascites sarcoma cells.
MedLine Citation:
PMID:  8397029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The organization of RSV genes present in the mouse ascites sarcoma cells was analysed. The transformed cells kept in vivo and in vitro for a long time continued to contain intact RSV genome and the cellular integration site was unchanged. RSV was recovered by transfection of chick embryo cells with these cellular DNA. As these cells, especially in ascites form, grow very rapidly and it is easy to obtain a large amount of cells at a time, they are useful for further study as RSV-transformants derived from mouse cells.
Authors:
H Ogura; M Imura; T Fujiwara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cellular and molecular biology (Noisy-le-Grand, France)     Volume:  39     ISSN:  0145-5680     ISO Abbreviation:  Cell. Mol. Biol. (Noisy-le-grand)     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1993-10-19     Completed Date:  1993-10-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9216789     Medline TA:  Cell Mol Biol (Noisy-le-grand)     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  503-7     Citation Subset:  IM    
Affiliation:
Department of Molecular Virology, Okayama University Medical School, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Avian Sarcoma Viruses / genetics*
Chick Embryo
DNA / isolation & purification
DNA, Neoplasm / isolation & purification
DNA, Viral / isolation & purification
Genes, src*
Genome, Viral*
Liver / metabolism
Mice
Mice, Inbred C3H
Restriction Mapping
Sarcoma, Experimental / genetics,  microbiology*
Transfection
Tumor Cells, Cultured
Virus Integration*
Chemical
Reg. No./Substance:
0/DNA, Neoplasm; 0/DNA, Viral; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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